In vitro studies with analogs related to ENMD-1420 showed that the Z isomer is more potent than the E isomer for antiproliferative activity. 与ENMD-1420相关的类似物体外研究显示在抗增殖活性方面Z异构体强于E异构体。
Objective: To establish the UV Spectrophotometry method of the determination of Prostaglandins E 1 for Injection by the method of isomer alkali. 目的:采用碱异构化法对注射用前列腺素E1进行含量测定。
Results: The method was proved to be selective for separation of cefdinir, its by-products, degradation products and E-isomer. 结果:头孢地尼与其副产物、降解产物及E异构体分离良好。
A sensitive and specific identification method of E isomer impurity in raw drug of Z cefepime dihydrochloride was established with high performance liquid chromatography/ tandem-time of flight ( HPLC/ ( Q-TOF)) mass spectrometry technology. 采用高效液相色谱/串联质谱技术建立了快速鉴定Z型盐酸头孢吡肟原料药中E型异构体杂质的新方法。
OBJECTIVE: To establish a sensitive method for the determination of roxithromycin ( E Rox) and its active metabolite,( 9Z) epimeric isomer ( Z Rox). 目的:建立灵敏专一的分析方法,测定人尿样中的罗红霉素(E-Rox)及其活性代谢产物Z-Rox。